Aims | Overview | Use Cases: | Example: Investigate the Importance of Eplet Mismatch in Retrospective Transplant Cohort | Step 1: Import recipient and donor typing data. We have an example cohort that can be loaded into the environment with the following code. This is A cohort of 14 recipients with donor and recipient high resolution HLA typing data for HLA Class I (A, B, C) and HLA Class II (DRB1, DRB3/4/5, and DQb and DQb). | Step 2: Calculate MHCI mismatch, pull information from result using single and overall outputs. | Example 1 - MHC-I | Step 3: Calculate MHCII mismatch and DRDQ risk score, pull information from result using single and overall outputs. | Step 4: Use visuals to examine the data. | Sources | MatchMaker Logic:

Vignette Aims | Load Test Data Set | Generate List of Possible Haplotypes and Sort Most likely Pairs | Impute high-resolution data | Notes: